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Free consultation
We go through your symptoms, health and medicines, and what you’ve already tried. We examine the joint and scan it with ultrasound, and look at any X-rays or MRI scans you bring.
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Durolane® is a long-acting form of hyaluronic acid, given as one injection into an arthritic knee or hip. At Vale it’s placed under ultrasound guidance, after a free consultation.
Free consultation, with no obligation · £350 per joint
Osteoarthritis is the most common reason for a painful knee or hip in later life. The cartilage covering the bone ends wears thinner, and the joint lining can become inflamed.
The fluid inside the joint changes too. It loses some of its hyaluronic acid, the substance that makes it thick and slippery, so it protects the joint less well.
Strengthening exercise, staying active and keeping to a healthy weight help most people. When pain still gets in the way, an injection is one option to consider.
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Durolane® contains 60 mg of hyaluronic acid in a 3 ml syringe. It’s made by fermentation, not from animal tissue, so it’s suitable if you have a poultry or egg allergy.
Its hyaluronic acid is lightly cross-linked, a process the manufacturer calls NASHA. This makes the gel more stable, so it stays in the joint longer than ordinary hyaluronic acid. That’s why a full treatment is one injection rather than a weekly course.
Drawn from published trials. Results differ between people, and some notice little change.
One appointment for the treatment, rather than three to five weekly visits.
Durolane® can be used in either joint, with ultrasound guiding the needle.
In a trial, its benefit held up better at six months than a steroid injection.
No anaesthetic or recovery period. Most people carry on with their day.
The gel restores some of the thickness the joint fluid has lost. Because it’s stabilised, it’s cleared from the joint more slowly than ordinary hyaluronic acid.
Hyaluronic acid may also calm inflammation in the joint lining, which could help explain why relief can last for months.
In osteoarthritis the fluid becomes watery and protects the cartilage less well.
Durolane® adds a dose of stabilised hyaluronic acid directly into the joint.
Thicker fluid may mean smoother movement and less pain when you put weight through the joint.
Durolane® is mainly used for mild to moderate osteoarthritis of the knee or hip.
It may suit you if the joint aches with walking or keeps you awake, and exercise and painkillers haven’t been enough. Some people choose it because they want to avoid repeated steroid injections, or because they’re not ready for surgery.
It’s less likely to help when the joint is badly worn, with bone rubbing on bone. In that case, we’ll talk you through other options, such as Arthrosamid® for the knee, or referral for a surgical opinion.
The most useful Durolane® study compared it directly with a steroid injection in 442 people with knee osteoarthritis [1].
Research on hyaluronic acid as a whole is more mixed. A Cochrane review found it improved knee pain compared with placebo [2], but NICE advises the NHS not to offer these injections, judging the overall benefit too small [3].
In short, some people get worthwhile relief for months, and others notice little. We’ll tell you honestly whether your joint looks like a good candidate.
| Durolane® | Ostenil® Plus | Cingal® | Cortisone | |
|---|---|---|---|---|
| What it is | Stabilised hyaluronic acid | Hyaluronic acid with mannitol | Hyaluronic acid with a steroid | Steroid |
| Joints | Knee or hip | Knee, hip and others | Knee | Many |
| Relief starts | Over a few weeks | Over 2–4 weeks | Within days | Within days |
| Price at Vale | £350 | £300 | £400 | £250 |
If you need relief quickly, Cingal® or a cortisone injection may suit you better. If cost matters, Ostenil® Plus is a single-injection alternative.
Mild soreness for a day or two is common. Contact us, or seek urgent medical advice, if the joint becomes increasingly hot, red, swollen and painful, or you feel feverish or unwell. These can be signs of infection, which is rare but needs prompt treatment.

Injection Therapist and Chiropractor, Clinic Director
GCC 03996

Doctor, Sport & Exercise Medicine
GMC 7689922



I first saw Gary for a consultation regarding the arthritis in my knees with a view to having a hyaluronic acid injection. Gary was extremely knowledgeable and went through all the options before suggesting which would be the best option for me.
My mum had acute knee pain which has been treated at the clinic, she now has much better mobility and positive outlook due to the treatment received. Gary has been so helpful and supportive throughout the consultation and treatment.
I recently had an ultrasound guided cortisone injection with Gary… Gary took the time to explain everything clearly before the procedure which really put me at ease, not easy when you’re not a fan of needles! The process itself was essentially pain free.
Gary helped me with my frozen shoulder. He was very thorough, professional and informative. I was given a cortisone injection, which he talked me through. During the procedure he was calming and efficient.
I cannot thank Gary and Gabriel enough for the stem cell treatment they gave me. When I started my treatment my tendonitis was so bad in my elbows that I couldn’t carry my little children, drive the car or do my day job without getting in severe pain.
Real Google reviews, shortened. Individual results vary. Read all our reviews ↗
You’ll feel a sharp scratch and some pressure as the gel goes in. A hip injection can feel deeper, but ultrasound guidance helps keep it quick.
Some people have soreness, warmth or swelling in the joint for a day or two. Infection is rare but needs prompt treatment, so we’ll tell you what to watch for. We go through your health and medicines at your consultation.
Durolane® isn’t a quick fix. Any improvement usually builds over the first few weeks.
In a large trial, the average benefit was still present at six months. Some people do better than that, and some notice little difference.
Yes, if the first one helped. We’ll review how long the benefit lasted before recommending a repeat.
Usually not. NICE, which advises the NHS in England, doesn’t recommend hyaluronic acid injections for osteoarthritis, so they’re mainly available privately.
Find out if Durolane® suits your knee or hip at a free consultation.
Written by Gary Edwards, Injection Therapist (PG Cert Injection Therapy) and Chiropractor (GCC 03996). Last updated 15 October 2026.